Control of disease is conducted by an integrated management based on the treatment with antibiotics or copper derivatives combined with the use of appropriate cultural measures and with biocontrol agents. The causal agent is Erwinia amylovora that infects mainly apple and pear as well as a broad range of woody ornamental plants. amylovora and provide the basis for developing better formulations of antibacterial peptides for plant protection.įire blight is an economically important disease affecting rosaceous plants. The combination of BP100 with lysozyme showed synergism on the bactericidal activity against E. The results obtained in vitro were confirmed in leaf infection bioassays. Combination of BP100 with lysozyme reduced the time required to achieve cell death and the minimal inhibitory concentration (MIC), and increased the activity of BP100 in the presence of leaf extracts even when the peptide was applied at low doses. amylovora that was associated to the increase of cell membrane damage and to the reduction of cell metabolism. We showed a significant increase of the antimicrobial activity against E. The combination of a synhetic multifunctional undecapeptide (BP100) with lysozyme produces a synergistic effect. We expected that the combination of BP100 with lysozyme may produce a synergistic effect, enhancing its activity and reducing the effective concentration needed for fire blight control. This is a limitation beause of the high cost of synthesis of this compound. However, the peptide concentration required for an effective control of infections in planta is too high due to some inactivation by tissue components. Moreover, BP100 showed bacteriolytic activity, moderate susceptibility to protease degradation and low toxicity. BP100, a synthetic linear undecapeptide (KKLFKKILKYL-NH 2), has been reported to be effective against E. ![]() Antimicrobial peptides (AMPs) have been proposed as a new compounds suitable for plant disease control. ![]() The causal agent is the bacteria Erwinia amylovora which is poorly controlled with the use of conventional bactericides and biopesticides. ![]() Fire blight is an important disease affecting rosaceous plants.
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